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    Tuesday, March 3
    Hywhos – Health, Nutrition & Wellness Blog
    Home»Healthy Habits»Antidepressants and Emotional Blunting: Causes and Treatment
    Healthy Habits

    Antidepressants and Emotional Blunting: Causes and Treatment

    8okaybaby@gmail.comBy 8okaybaby@gmail.comSeptember 29, 2025No Comments8 Mins Read
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    Antidepressants and Emotional Blunting: Causes and Treatment
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    Information in this article might be triggering to some people. If you are having suicidal thoughts, contact the National Suicide Prevention Lifeline at 988 for support and assistance from a trained counselor. If you or a loved one are in immediate danger, call 911.

    For more mental health resources, see our National Helpline Database.

    Key Takeaways

    • Emotional blunting happens to many who take antidepressants, making emotions feel dull or numb.
    • Exercise, healthy eating, and no alcohol can help lift your mood and ease emotional blunting.
    • Talk to your doctor if you feel numb on your medication, as they may adjust your dose or switch your prescription.

    When first starting antidepressants, you may not feel like yourself. Though your depression symptoms might have improved, feelings of extreme sadness can sometimes be replaced by an emotional numbness in which you are neither able to cry nor enjoy a real belly laugh.

    If you feel this way, you are definitely not alone. There’s a term used to describe this feeling—called emotional blunting—which aptly captures the dulled emotional state many people experience when taking antidepressants.

    While emotional blunting may make you want to stop your antidepressant medications, it’s important to know that there are things you can do to help overcome this effect and still continue your depression treatment. Learn more about why antidepressants can blunt emotions, as well as what actions you can take to start to feel like yourself again.

    Never stop taking an antidepressant without speaking to your healthcare provider first. They may change the dose or switch medications to help combat any bothersome side effects you may be experiencing while continuing to treat your depression.

    Symptoms of Emotional Blunting

    Emotional blunting means that your feelings and emotions are so dulled that you neither feel up nor down. You simply feel “blah.” People who experience emotional blunting will often report:

    • Being less able to laugh or cry, even when appropriate
    • Feeling distant from the world around them
    • Feeling less empathy for others
    • Loss of motivation and drive
    • Not being able to respond with the same level of enjoyment that they normally would

    Emotional blunting reduces your range of emotions, causing you to feel less love, fear, affection, or anger.

    Prevalence of Emotional Blunting

    A study from the University of Oxford found that 46% of antidepressant users experienced emotional blunting during treatment. According to the research, the antidepressants most commonly associated with emotional blunting are:

    By and large, those who no longer needed antidepressants experienced a reversal of emotional blunting, confirming the role that these drugs play in this side effect.

    Though the percentage of people who experienced emotional blunting was similar between the three drug classes, there were variations. On the one end, 33% experienced emotional blunting while on Wellbutrin (bupropion) while, on the other end, 75% experienced the same effect on Cymbalta (duloxetine hydrochloride).

    Wellbutrin is a different class of drug known as a dopamine and norepinephrine reuptake inhibitor. Unlike the others, it does not target a chemical transmitter in the brain—known as serotonin—that all of the other drugs do. This suggests that the inhibition of serotonin may be one of the prime causes of emotional blunting.

    Click Play to Learn More About Emotional Blunting

    Other Study Findings

    According to the Oxford study, men experienced blunting more than women at 54% vs. 44%, respectively. Moreover, the severity of depression before treatment directly corresponded to the severity of emotional blunting during treatment.

    The study also found that not everyone viewed emotional blunting in the same way. Of the 819 people included, 38% regarded the blunting of their emotions as a positive outcome of treatment, while 37% viewed it negatively. Generally speaking, those with more severe blunting symptoms viewed it more negatively.

    Supporting Evidence

    Other research has found similar results. For example, an online survey of 1,431 antidepressant users from 38 countries aimed to identify the most common adverse side effects of treatment. “Feeling emotionally numb” was ranked number one, with 71% experiencing this symptom.

    “Feeling foggy or detached” was a close second at 70% and “feeling not like myself” was third with 66%. The study didn’t specify which types of antidepressants resulted in these effects.

    A smaller study from New Zealand involving 180 people on long-term antidepressant therapy found that 64.5% experienced emotional blunting. Related side effects included sexual difficulties (71.8%), not feeling like themselves (54.4%), and a reduction in positive feelings (45.6%).

    Additionally, a Canadian study involving 896 participants, 49.9% of whom had major depressive disorder (MDD) and 50.1% of whom had bipolar disorder (BP), found that emotional blunting was one of the main reasons for the discontinuation of therapy. After weight gain and excessive sleepiness, emotional blunting ranked third in the reasons to stop treatment among people with MDD.

    Causes of Emotional Blunting

    Given that not everyone on antidepressants develops emotional blunting, it has been difficult for scientists to tease out a precise reason for this effect. Some experts have even questioned whether blunting is a side effect of antidepressant treatment or perhaps a partial failure of the drug itself.

    While it would seem fair to assume that serotonin plays a role in the effect (given the lower incidence among Wellbutrin users), most scientists believe that a single hormone cannot be to blame.

    It is likely that the imbalance of all three key neurotransmitters—serotonin, dopamine, and norepinephrine—may trigger the effect of emotional blunting and that those with an underlying hormonal deficit will fare worse.

    Others still have suggested that emotional blunting is more of a symptom revealed, meaning that once the antidepressants are able to alleviate depression, the underlying symptoms of emotional blunting are revealed rather than caused. Much more research is needed before any conclusions can be drawn.

    Treatment for Emotional Blunting

    The good news is that emotional blunting can be treated. Some of the options to consider include:

    • Live a healthy lifestyle. Engaging in exercise stimulates serotonin and elevates mood. Eating healthier and avoiding alcohol (a mood depressant) can also help.
    • Ask about medication changes. If you experience emotional blunting, your healthcare provider may lower your dose or switch you to a different antidepressant (say, from an SSRI to an SNRI). They may also be able to add other medication to offset the emotional blunting.
    • Work with your therapist to find ways to elevate your mood. There may be a psychological component to your condition as well as a pharmaceutical one.

    Do Not Stop Taking Your Medication

    If you find the emotional blunting intolerable, do not stop treatment without first speaking with your physician. Doing so may lead to a rebound of depression symptoms or trigger the opposite effect, including anxiety, agitation, and sleeplessness.

    Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

    1. Cronquist Christensen M, Ren H, Fagiolini A. Emotional blunting in patients with depression. Part I: clinical characteristics. Ann Gen Psychiatry. 2022;21:10. doi:10.1186/s12291-022-00387-1

    2. Aydemir EO, Asian E, Yazici MK. SSRI induced apathy syndrome. Psychiatry Behav Sci. 2018;8(2):63-70.  doi:10.5455/PBS.20180115111230

    3. Ma H, Cai M, Wang H. Emotional blunting in patients with major depressive disorder: A brief non-systematic review of current research. Front Psychiatry. 2021;12:792960. doi:10.3389/fpsyt.2021.792960

    4. Goodwin GM, Price J, De Bodinat C, Laredo J. Emotional blunting with antidepressant treatments: A survey among depressed patients. J Affect Disord. 2017;221:31-35. doi:10.1016/j.jad.2017.05.048

    5. Patel K, Allen S, Haque MN, Angelescu I, Baumeister D, Tracy DK. Bupropion: a systematic review and meta-analysis of effectiveness as an antidepressant. Ther Adv Psychopharmacol. 2016;6(2):99-144. doi:10.1177/2045125316629071

    6. Read J, Williams J. Adverse effects of antidepressants reported by a large international cohort: Emotional blunting, suicidality, and withdrawal effects. Curr Drug Safety. 2018;13(3):176–186. doi:10.2174/1574886313666180605095130

    7. Cartwright C, Gibson K, Read J, Cowan O, Dehar T. Long-term antidepressant use: Patient perspectives of benefits and adverse effects. Patient Pref Adher. 2016;10:1401–1407. doi:10.2147/PPA.S110632

    8. Rosenblat JD, Simon GE, Sachs GS, et al. Treatment effectiveness and tolerability outcomes that are most important to individuals with bipolar and unipolar depression. J Affect Disord. 2019;243:116-120. doi:10.1016/j.jad.2018.09.027

    9. Sadock BJ, Sadock VA, Ruiz P. Kaplan & Sadock’s Concise Textbook of Clinical Psychiatry (4th edition).

    10. Jones JD, Butterfield LC, Song W, et al. Anxiety and depression are better correlates of Parkinson’s disease quality of life than apathy. J Neuropsychiatry Clin Neurosci. 2015;27(3):213-8. doi:10.1176/appi.neuropsych.13120380

    11. Melancon MO, Lorrain D, Dionne IJ. Changes in markers of brain serotonin activity in response to chronic exercise in senior men. App Physiol Nutr Metab. 2014;39(11):1250-6. doi:10.1139/apnm-2014-0092

    12. Harvard Health Publishing. Going off antidepressants.

    Additional Reading

    • Rosenblat JD, Simon GE, Sachs GS, et al. Treatment effectiveness and tolerability outcomes that are most important to individuals with bipolar and unipolar depression. J Affect Disord. 2019;243:116-120. doi:10.1016/j.jad.2018.09.027

    By Nancy Schimelpfening

    Nancy Schimelpfening, MS is the administrator for the non-profit depression support group Depression Sanctuary. Nancy has a lifetime of experience with depression, experiencing firsthand how devastating this illness can be.  

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