Centered in the prefrontal cortex, this pathway acts like the brain’s dimmer switch. When it’s functioning well, it regulates emotions, quiets catastrophizing, and helps the body return to baseline. But when it’s compromised, by lack of sleep, inflammation, substance use, trauma, or even chronic negativity, the brain loses its natural ability to turn down the intensity.
Your Brain Might Be The Missing Link In Chronic Pain — Here’s Why
